KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCB1
All Species:
20
Human Site:
S661
Identified Species:
36.67
UniProt:
P08183
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P08183
NP_000918.2
1280
141479
S661
S
S
N
D
S
R
S
S
L
I
R
K
R
S
T
Chimpanzee
Pan troglodytes
XP_519183
1280
141455
S661
S
S
N
D
S
R
S
S
L
I
R
K
R
S
T
Rhesus Macaque
Macaca mulatta
NP_001028059
1283
141504
S664
S
S
H
D
S
G
S
S
L
I
R
K
R
S
T
Dog
Lupus familis
XP_539461
1269
140189
S654
L
I
P
K
S
S
K
S
L
I
N
S
K
Y
K
Cat
Felis silvestris
Mouse
Mus musculus
P21447
1276
140628
S657
S
S
K
D
S
G
S
S
L
I
R
R
R
S
T
Rat
Rattus norvegicus
P43245
1277
141369
S659
L
T
S
E
E
S
K
S
P
L
I
R
R
S
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508941
1368
147746
N750
N
G
T
R
M
S
S
N
G
H
V
F
R
R
S
Chicken
Gallus gallus
XP_418636
1307
144961
G689
L
N
G
S
V
L
T
G
Q
K
R
Q
S
T
R
Frog
Xenopus laevis
NP_001081394
1287
141487
R671
H
T
H
S
N
L
V
R
R
K
S
S
R
N
T
Zebra Danio
Brachydanio rerio
XP_001922717
1340
147081
K724
L
E
R
G
S
F
R
K
S
L
K
R
S
S
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q00748
1302
143766
S674
F
E
K
S
F
E
T
S
P
L
N
F
E
K
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34712
1321
145045
R685
S
E
H
E
G
L
S
R
Q
A
S
E
M
D
D
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O80725
1286
139009
S652
Q
S
S
L
R
K
S
S
L
G
R
S
L
S
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
96
55.7
N.A.
87.1
80.6
N.A.
62.1
69.6
67.6
56
N.A.
41.1
N.A.
44.5
N.A.
Protein Similarity:
100
99.8
97.7
75.4
N.A.
93.3
90.1
N.A.
76.6
83.6
81.8
73.5
N.A.
60.4
N.A.
62.6
N.A.
P-Site Identity:
100
100
86.6
26.6
N.A.
80
20
N.A.
13.3
6.6
13.3
13.3
N.A.
6.6
N.A.
13.3
N.A.
P-Site Similarity:
100
100
93.3
33.3
N.A.
86.6
53.3
N.A.
33.3
33.3
40
33.3
N.A.
20
N.A.
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
41.2
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
62.5
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
53.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
31
0
0
0
0
0
0
0
0
0
8
8
% D
% Glu:
0
24
0
16
8
8
0
0
0
0
0
8
8
0
0
% E
% Phe:
8
0
0
0
8
8
0
0
0
0
0
16
0
0
0
% F
% Gly:
0
8
8
8
8
16
0
8
8
8
0
0
0
0
8
% G
% His:
8
0
24
0
0
0
0
0
0
8
0
0
0
0
0
% H
% Ile:
0
8
0
0
0
0
0
0
0
39
8
0
0
0
8
% I
% Lys:
0
0
16
8
0
8
16
8
0
16
8
24
8
8
24
% K
% Leu:
31
0
0
8
0
24
0
0
47
24
0
0
8
0
0
% L
% Met:
0
0
0
0
8
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
8
8
16
0
8
0
0
8
0
0
16
0
0
8
0
% N
% Pro:
0
0
8
0
0
0
0
0
16
0
0
0
0
0
0
% P
% Gln:
8
0
0
0
0
0
0
0
16
0
0
8
0
0
0
% Q
% Arg:
0
0
8
8
8
16
8
16
8
0
47
24
54
8
8
% R
% Ser:
39
39
16
24
47
24
54
62
8
0
16
24
16
54
8
% S
% Thr:
0
16
8
0
0
0
16
0
0
0
0
0
0
8
39
% T
% Val:
0
0
0
0
8
0
8
0
0
0
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _